Pharmacogenomic Genes

Genes Tested Menu

Pharmacogenomic testing may be used to help predict:

  • Which drug may work best for you
  • The proper dosage
  • Your risk for negative side effects

Currently, pharmacogenomic testing is done for genes that affect certain types of drugs, such as medications for treating depression, pain, and heart disease. It will be expanded to other genes as researchers learn more about how genomic differences affect the way medications work in the human body.

A person’s genes may determine what type of response they have to certain medications.

Pharmacogenomic Genes Tested

GeneCommon Drugs Metabolized
CYP2C19citalopram, escitalopram, pantoprazole, esomeprazole, omeprazole, clopidogrel
CYP2C9warfarin, ibuprofen, celecoxib, meloxicam
CYP2D6amitriptyline, nortriptyline, tramadol, codeine, atomoxetine
CYP3A5tacrolimus
CYP4F2warfarin
CYP2B6efavirenz
SLCO1B1simvastatin, atorvastatin, rosuvatatin
DPYDcapecitabine, fluorouracil
NUDT15azathioprine, mercaptopurine, thioguanine
TPMTazathioprine, mercaptopurine, thioguanine
UGT1A1atazanavir, irinotecan
VKORC1warfarin